Sermorelin Nasal Spray — 5mg

Sermorelin is a synthetic analog comprising the first 29 amino acids of endogenous GHRH — the shortest fragment retaining full signalling activity, which is why it is written GHRH(1-29). It sits in the GHRH class alongside Tesamorelin and is studied against GHS-R agonists like Ipamorelin because the two classes engage different receptors. This nasal atomiser format supplies the same research-grade Sermorelin stocked in vial form, packaged for intranasal research handling.

SHIPPED UNMIXED — AND WHY THAT MATTERS

Durham Peptides does not ship pre-diluted nasal sprays. Peptides in solution are materially less stable than in lyophilized form, so a bottle that is mixed at the warehouse begins losing potency the day it is filled and continues to do so in transit and in storage. Instead, the lyophilized peptide and the diluent travel separately and the researcher reconstitutes on arrival — which means full-strength material and a known, controlled in-use window rather than an unknown one.

Every nasal spray ships with sterile water preserved with 0.3% potassium sorbate, supplied specifically for this format. No separate bacteriostatic water purchase is required.

BENEFITS

• Ships unmixed — full-strength lyophilized material, not a solution degrading in transit

• Diluent included — sterile water with 0.3% potassium sorbate, no separate purchase needed

• Metered atomiser — consistent, repeatable delivery volume per actuation

• Defined fragment — GHRH(1-29), the shortest sequence retaining full signalling activity

• Verified identity — MS-confirmed against a Janoshik report you can check independently

WHAT RESEARCHERS LOOK AT

• GHRH receptor signalling in preclinical growth-hormone-axis models

• Whether the 1-29 fragment reproduces the activity of the full endogenous sequence

• Comparative behaviour against GHS-R agonists such as Ipamorelin, which act on a different receptor

• Intranasal versus parenteral delivery in comparative research models

• Post-reconstitution stability across the in-use window

QUICK SPECS

• Format: Metered nasal atomiser, supplied unmixed

• Form: Lyophilized peptide powder plus separate sterile diluent

• Net peptide per bottle: 5 mg

• Bottle volume: 10 mL

• Metered spray volume: 0.1 mL per actuation

• Sprays per bottle: approximately 100

• Concentration once reconstituted: 0.5 mg/mL

• Peptide per metered spray: 50 mcg (0.05 mg)

• Included diluent: Sterile water with 0.3% potassium sorbate

• Purity: ≥99% (HPLC verified)

• Identity: MS-verified (per COA)

• Storage: 2–8°C before and after reconstitution, protect from light

• Reconstitution: Diluent supplied — no separate bacteriostatic water required

IDENTITY BASICS

• Compound: Sermorelin, CAS 86168-78-7 (acetate salt form CAS 516482-86-3)

• Structure: GHRH(1-29) amide, 29-amino-acid growth-hormone-releasing hormone analog

• Molecular weight: Approx 3,358 Da (free base)

• Class: GHRH analog

WHY CHOOSE DURHAM PEPTIDES FOR NASAL SPRAYS?

• Shipped unmixed for freshness — not pre-diluted at the warehouse

• Sterile diluent included in every bottle

• Janoshik tested with independently verifiable COA keys

• Same-day shipping across Canada (orders before 5:00 PM EST)

• Free shipping on orders over $200 CAD

• 100% vegan — synthetically manufactured, no animal derivatives

• Transparent Canadian pricing, shown above in CAD

DOES THE NASAL SPRAY COME PRE-MIXED?

No, and that is deliberate. Peptides are materially less stable in solution than in lyophilized form, so a pre-diluted bottle starts losing potency the day it is filled. Durham Peptides ships the lyophilized peptide and the sterile diluent separately so the researcher reconstitutes on arrival — full-strength material, and a known in-use window rather than an unknown one.

DO I NEED TO BUY BACTERIOSTATIC WATER SEPARATELY?

No. Every nasal spray ships with its own diluent — sterile water preserved with 0.3% potassium sorbate, supplied specifically for the atomiser format. This differs from the lyophilized vials in our catalogue, which are reconstituted with bacteriostatic water sold separately.

NASAL SPRAY VS VIAL — WHICH SHOULD I CHOOSE?

Both supply the same research-grade Sermorelin. The vial — Sermorelin Acetate — 5mg — is the flexible option, since the researcher chooses the reconstitution volume and therefore the working concentration. The nasal atomiser is the convenience option, arriving with matched diluent and a metered actuator for consistent delivery volume. The choice depends on whether the protocol calls for a custom concentration or a repeatable fixed one.

WHAT IS SERMORELIN?

Sermorelin is a synthetic analog comprising the first 29 amino acids of endogenous GHRH — the shortest fragment that retains full signalling activity, hence the notation GHRH(1-29). It sits in the GHRH class alongside Tesamorelin, and is studied against GHS-R agonists such as Ipamorelin because the two classes engage different receptors.

HOW SHOULD IT BE STORED AFTER RECONSTITUTION?

Keep the bottle refrigerated at 2–8°C and protected from light both before and after reconstitution. Once reconstituted, use within an appropriate research timeframe — a peptide in solution has a materially shorter usable life than the sealed lyophilized material.

HOW IS IT SHIPPED IN CANADA?

Orders placed and paid before 5:00 PM EST ship the same business day via Canada Post Xpresspost with full tracking. Shipping is domestic from within Canada, so there are no customs delays or border holds.

IS THE COA VERIFIABLE?

Yes. Every batch is Janoshik-tested with a unique report key you can confirm independently — see our guide on how to verify a Janoshik unique key.

• For laboratory research use only.

• Not for human or veterinary use.

• Not intended for diagnosis, treatment, cure, or prevention of any disease.

• Use only in controlled laboratory settings by qualified personnel following appropriate safety procedures.