Sermorelin Nasal Spray — 5mg
Research-grade Sermorelin in a metered nasal atomiser format — 5mg lyophilized peptide supplied with sterile diluent for researcher reconstitution. Sermorelin is GHRH(1-29) amide, a 29-amino-acid growth-hormone-releasing hormone analog. 99%+ purity verified by an independent third-party lab via HPLC and mass spectrometry.
Ships unmixed — reconstitute on arrival for full-strength material.
For laboratory research use only.
Not for human or veterinary use.
Not intended for diagnosis, treatment, cure, or prevention of any disease.
Use only in controlled laboratory settings by qualified personnel following appropriate safety procedures.
Sermorelin is a synthetic analog comprising the first 29 amino acids of endogenous GHRH — the shortest fragment retaining full signalling activity, which is why it is written GHRH(1-29). It sits in the GHRH class alongside Tesamorelin and is studied against GHS-R agonists like Ipamorelin because the two classes engage different receptors. This nasal atomiser format supplies the same research-grade Sermorelin stocked in vial form, packaged for intranasal research handling.
SHIPPED UNMIXED — AND WHY THAT MATTERS
Durham Peptides does not ship pre-diluted nasal sprays. Peptides in solution are materially less stable than in lyophilized form, so a bottle that is mixed at the warehouse begins losing potency the day it is filled and continues to do so in transit and in storage. Instead, the lyophilized peptide and the diluent travel separately and the researcher reconstitutes on arrival — which means full-strength material and a known, controlled in-use window rather than an unknown one.
Every nasal spray ships with sterile water preserved with 0.3% potassium sorbate, supplied specifically for this format. No separate bacteriostatic water purchase is required.
BENEFITS
Ships unmixed — full-strength lyophilized material, not a solution degrading in transit
Diluent included — sterile water with 0.3% potassium sorbate, no separate purchase needed
Metered atomiser — consistent, repeatable delivery volume per actuation
Defined fragment — GHRH(1-29), the shortest sequence retaining full signalling activity
Verified identity — MS-confirmed against a third-party lab report you can check independently
WHAT RESEARCHERS LOOK AT
GHRH receptor signalling in preclinical growth-hormone-axis models
Whether the 1-29 fragment reproduces the activity of the full endogenous sequence
Comparative behaviour against GHS-R agonists such as Ipamorelin, which act on a different receptor
Intranasal versus parenteral delivery in comparative research models
Post-reconstitution stability across the in-use window
QUICK SPECS
Format: Metered nasal atomiser, supplied unmixed
Form: Lyophilized peptide powder plus separate sterile diluent
Net peptide per bottle: 5 mg
Bottle volume: 10 mL
Metered spray volume: 0.1 mL per actuation
Sprays per bottle: approximately 100
Concentration once reconstituted: 0.5 mg/mL
Peptide per metered spray: 50 mcg (0.05 mg)
Included diluent: Sterile water with 0.3% potassium sorbate
Purity: ≥99% (HPLC verified)
Identity: MS-verified (per COA)
Storage: 2–8°C before and after reconstitution, protect from light
Reconstitution: Diluent supplied — no separate bacteriostatic water required
IDENTITY BASICS
Compound: Sermorelin, CAS 86168-78-7 (acetate salt form CAS 516482-86-3)
Structure: GHRH(1-29) amide, 29-amino-acid growth-hormone-releasing hormone analog
Molecular weight: Approx 3,358 Da (free base)
Class: GHRH analog
WHY CHOOSE DURHAM PEPTIDES FOR NASAL SPRAYS?
Shipped unmixed for freshness — not pre-diluted at the warehouse
Sterile diluent included in every bottle
independently lab-tested with verifiable COA keys
Same-day shipping across Canada (orders before 4:00 PM EST)
Free shipping on orders over $200 CAD
Transparent Canadian pricing, shown above in CAD
DOES THE NASAL SPRAY COME PRE-MIXED?
No, and that is deliberate. Peptides are materially less stable in solution than in lyophilized form, so a pre-diluted bottle starts losing potency the day it is filled. Durham Peptides ships the lyophilized peptide and the sterile diluent separately so the researcher reconstitutes on arrival — full-strength material, and a known in-use window rather than an unknown one.
DO I NEED TO BUY BACTERIOSTATIC WATER SEPARATELY?
No. Every nasal spray ships with its own diluent — sterile water preserved with 0.3% potassium sorbate, supplied specifically for the atomiser format. This differs from the lyophilized vials in our catalogue, which are reconstituted with bacteriostatic water sold separately.
NASAL SPRAY VS VIAL — WHICH SHOULD I CHOOSE?
Both supply the same research-grade Sermorelin. The vial — Sermorelin Acetate — 5mg — is the flexible option, since the researcher chooses the reconstitution volume and therefore the working concentration. The nasal atomiser is the convenience option, arriving with matched diluent and a metered actuator for consistent delivery volume. The choice depends on whether the protocol calls for a custom concentration or a repeatable fixed one.
WHAT IS SERMORELIN?
Sermorelin is a synthetic analog comprising the first 29 amino acids of endogenous GHRH — the shortest fragment that retains full signalling activity, hence the notation GHRH(1-29). It sits in the GHRH class alongside Tesamorelin, and is studied against GHS-R agonists such as Ipamorelin because the two classes engage different receptors.
HOW SHOULD IT BE STORED AFTER RECONSTITUTION?
Keep the bottle refrigerated at 2–8°C and protected from light both before and after reconstitution. Once reconstituted, use within an appropriate research timeframe — a peptide in solution has a materially shorter usable life than the sealed lyophilized material.
HOW IS IT SHIPPED IN CANADA?
Orders placed and paid before 4:00 PM EST ship the same business day via Canada Post Xpresspost with full tracking. Shipping is domestic from within Canada, so there are no customs delays or border holds.
IS THE COA VERIFIABLE?
Yes. Every batch is independently lab-tested with a unique report key you can confirm independently — see our guide on how to verify a lab report key.
For laboratory research use only.
Not for human or veterinary use.
Not intended for diagnosis, treatment, cure, or prevention of any disease.
Use only in controlled laboratory settings by qualified personnel following appropriate safety procedures.
Volume discounts apply to your whole order, not to a single item. Enter the code at checkout.
Spend $200 or more — 10% off with code VOLUME10
Spend $500 or more — 15% off with code VOLUME15
Spend $1,000 or more — 20% off with code VOLUME20
Spend $2,000 or more — 25% off with code VOLUME25
The thresholds are worth more than they look. A $499 order costs you $449. Add one more $20 vial to reach $500 and you pay $425 — more product, $24 less. Free shipping over $200.
Ordering at volume? The full catalogue is available at wholesale pricing through a five-tier programme.
Minimum 10 units per product, any mix of products in one order
Accounts open at $2,000 per order
Tiers are set on 12-month volume and move up automatically
Canadian stock, same-day dispatch, shipping included
Apply at durhampeptides.ca/wholesale and we come back within one business day. Single vials and multi-packs on this page are available to everyone at the prices shown — no account needed.
