PT-141 Nasal Spray — 10mg
Research-grade PT-141 (Bremelanotide) in a metered nasal atomiser format — 10mg lyophilized peptide supplied with sterile diluent for researcher reconstitution. PT-141 is a cyclic heptapeptide melanocortin receptor agonist. 99%+ purity verified by Janoshik Analytical via HPLC and mass spectrometry.
Ships unmixed — reconstitute on arrival for full-strength material.
For laboratory research use only.
Not for human or veterinary use.
Not intended for diagnosis, treatment, cure, or prevention of any disease.
Use only in controlled laboratory settings by qualified personnel following appropriate safety procedures.
PT-141, also known as Bremelanotide, is a cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone and acts as an agonist at melanocortin receptors. It is one of the compounds most commonly studied via the intranasal route, which is why the atomiser format is a natural fit rather than an afterthought.
SHIPPED UNMIXED — AND WHY THAT MATTERS
Durham Peptides does not ship pre-diluted nasal sprays. Peptides in solution are materially less stable than in lyophilized form, so a bottle that is mixed at the warehouse begins losing potency the day it is filled and continues to do so in transit and in storage. Instead, the lyophilized peptide and the diluent travel separately and the researcher reconstitutes on arrival — which means full-strength material and a known, controlled in-use window rather than an unknown one.
Every nasal spray ships with sterile water preserved with 0.3% potassium sorbate, supplied specifically for this format. No separate bacteriostatic water purchase is required.
BENEFITS
Ships unmixed — full-strength lyophilized material, not a solution degrading in transit
Diluent included — sterile water with 0.3% potassium sorbate, no separate purchase needed
Metered atomiser — consistent, repeatable delivery volume per actuation
Route-appropriate — intranasal is the conventional research route for this compound
Verified identity — MS-confirmed against a Janoshik report you can check independently
WHAT RESEARCHERS LOOK AT
Melanocortin receptor subtype selectivity and binding affinity
Central versus peripheral signalling in preclinical models
Intranasal versus parenteral delivery in comparative research models
Structure-activity relationships of the cyclic heptapeptide backbone
Post-reconstitution stability across the in-use window
QUICK SPECS
Format: Metered nasal atomiser, supplied unmixed
Form: Lyophilized peptide powder plus separate sterile diluent
Net peptide per bottle: 10 mg
Bottle volume: 10 mL
Metered spray volume: 0.1 mL per actuation
Sprays per bottle: approximately 100
Concentration once reconstituted: 1 mg/mL
Peptide per metered spray: 100 mcg (0.1 mg)
Included diluent: Sterile water with 0.3% potassium sorbate
Purity: ≥99% (HPLC verified)
Identity: MS-verified (per COA)
Storage: 2–8°C before and after reconstitution, protect from light
Reconstitution: Diluent supplied — no separate bacteriostatic water required
IDENTITY BASICS
Compound: PT-141 (Bremelanotide), CAS 189691-06-3
Class: Cyclic heptapeptide melanocortin receptor agonist
Also written as: Bremelanotide, PT 141
WHY CHOOSE DURHAM PEPTIDES FOR NASAL SPRAYS?
Shipped unmixed for freshness — not pre-diluted at the warehouse
Sterile diluent included in every bottle
Janoshik tested with independently verifiable COA keys
PT-141 vials also stocked for researchers who prefer custom concentrations
Same-day shipping across Canada (orders before 5:00 PM EST)
Free shipping on orders over $200 CAD
Transparent Canadian pricing, shown above in CAD
DOES THE NASAL SPRAY COME PRE-MIXED?
No, and that is deliberate. Peptides are materially less stable in solution than in lyophilized form, so a pre-diluted bottle starts losing potency the day it is filled. Durham Peptides ships the lyophilized peptide and the sterile diluent separately so the researcher reconstitutes on arrival — full-strength material, and a known in-use window rather than an unknown one.
DO I NEED TO BUY BACTERIOSTATIC WATER SEPARATELY?
No. Every nasal spray ships with its own diluent — sterile water preserved with 0.3% potassium sorbate, supplied specifically for the atomiser format. This differs from the lyophilized vials in our catalogue, which are reconstituted with bacteriostatic water sold separately.
WHAT IS PT-141?
PT-141, also called Bremelanotide, is a cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone that acts as an agonist at melanocortin receptors. It is studied in research models for receptor subtype selectivity and downstream signalling.
NASAL SPRAY VS VIAL — WHICH SHOULD I CHOOSE?
Both supply the same research-grade PT-141. The vial — PT-141 (Bremelanotide) — 10mg — is the flexible option, since the researcher chooses the reconstitution volume and therefore the working concentration. The nasal atomiser is the convenience option, arriving with matched diluent and a metered actuator for consistent delivery volume. The choice depends on whether the protocol calls for a custom concentration or a repeatable fixed one.
HOW SHOULD IT BE STORED AFTER RECONSTITUTION?
Keep the bottle refrigerated at 2–8°C and protected from light both before and after reconstitution. Once reconstituted, use within an appropriate research timeframe — a peptide in solution has a materially shorter usable life than the sealed lyophilized material.
HOW IS IT SHIPPED IN CANADA?
Orders placed and paid before 5:00 PM EST ship the same business day via Canada Post Xpresspost with full tracking. Shipping is domestic from within Canada, so there are no customs delays or border holds.
IS THE COA VERIFIABLE?
Yes. Every batch is Janoshik-tested with a unique report key you can confirm independently — see our guide on how to verify a Janoshik unique key.
For laboratory research use only.
Not for human or veterinary use.
Not intended for diagnosis, treatment, cure, or prevention of any disease.
Use only in controlled laboratory settings by qualified personnel following appropriate safety procedures.
