
NAD+ Nasal Spray — 500mg
Research-grade NAD+ (nicotinamide adenine dinucleotide) in a metered nasal atomiser format — 500mg lyophilized material supplied with sterile diluent for researcher reconstitution. NAD+ is a coenzyme central to cellular redox metabolism. 99%+ purity verified by Janoshik Analytical via HPLC and mass spectrometry.
Ships unmixed — reconstitute on arrival for full-strength material.
For laboratory research use only.
Not for human or veterinary use.
Not intended for diagnosis, treatment, cure, or prevention of any disease.
Use only in controlled laboratory settings by qualified personnel following appropriate safety procedures.
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every living cell, where it functions as the central electron carrier in redox metabolism and as a substrate for sirtuins and PARP enzymes. Note that unlike most of this catalogue it is not a peptide — it is a dinucleotide, which is why it is described here by molecular identity rather than amino acid sequence.
SHIPPED UNMIXED — AND WHY THAT MATTERS
Durham Peptides does not ship pre-diluted nasal sprays. Compounds in solution are materially less stable than in lyophilized form, so a bottle that is mixed at the warehouse begins losing potency the day it is filled and continues to do so in transit and in storage. Instead, the lyophilized material and the diluent travel separately and the researcher reconstitutes on arrival — which means full-strength material and a known, controlled in-use window rather than an unknown one.
Every nasal spray ships with sterile water preserved with 0.3% potassium sorbate, supplied specifically for this format. No separate bacteriostatic water purchase is required.
BENEFITS
Ships unmixed — full-strength lyophilized material, not a solution degrading in transit
Diluent included — sterile water with 0.3% potassium sorbate, no separate purchase needed
Generous 500mg loading — suits extended or multi-arm protocols
Metered atomiser — consistent, repeatable delivery volume per actuation
Verified identity — MS-confirmed against a Janoshik report you can check independently
WHAT RESEARCHERS LOOK AT
Cellular NAD+ pools and the salvage pathway
Sirtuin and PARP enzyme activity as NAD+-dependent processes
Mitochondrial redox balance and electron transport
Comparative work against NNMT inhibition approaches such as 5-Amino-1MQ
Post-reconstitution stability across the in-use window
QUICK SPECS
Format: Metered nasal atomiser, supplied unmixed
Form: Lyophilized powder plus separate sterile diluent
Net per bottle: 500 mg
Bottle volume: 10 mL
Metered spray volume: 0.1 mL per actuation
Sprays per bottle: approximately 100
Concentration once reconstituted: 50 mg/mL
NAD+ per metered spray: 5 mg
Included diluent: Sterile water with 0.3% potassium sorbate
Purity: ≥99% (HPLC verified)
Identity: MS-verified (per COA)
Storage: 2–8°C before and after reconstitution, protect from light
Reconstitution: Diluent supplied — no separate bacteriostatic water required
IDENTITY BASICS
Compound: Nicotinamide adenine dinucleotide (NAD+), CAS 53-84-9
Class: Dinucleotide coenzyme — not a peptide
Also written as: NAD, beta-NAD, nicotinamide adenine dinucleotide
WHY CHOOSE DURHAM PEPTIDES FOR NASAL SPRAYS?
Shipped unmixed for freshness — not pre-diluted at the warehouse
Sterile diluent included in every bottle
Janoshik tested with independently verifiable COA keys
NAD+ vials in 500mg and 1000mg also stocked for other research formats
Same-day shipping across Canada (orders before 5:00 PM EST)
Free shipping on orders over $200 CAD
Transparent Canadian pricing, shown above in CAD
DOES THE NASAL SPRAY COME PRE-MIXED?
No, and that is deliberate. Compounds are materially less stable in solution than in lyophilized form, so a pre-diluted bottle starts losing potency the day it is filled. Durham Peptides ships the lyophilized material and the sterile diluent separately so the researcher reconstitutes on arrival — full-strength material, and a known in-use window rather than an unknown one.
DO I NEED TO BUY BACTERIOSTATIC WATER SEPARATELY?
No. Every nasal spray ships with its own diluent — sterile water preserved with 0.3% potassium sorbate, supplied specifically for the atomiser format. This differs from the lyophilized vials in our catalogue, which are reconstituted with bacteriostatic water sold separately.
IS NAD+ A PEPTIDE?
No. Despite being sold alongside research peptides, NAD+ is a dinucleotide coenzyme, not a peptide. It has no amino acid sequence and is described by molecular identity instead.
NASAL SPRAY VS VIAL — WHICH SHOULD I CHOOSE?
Both supply the same research-grade NAD+. The vial — NAD+ — 500mg — is the flexible option, since the researcher chooses the reconstitution volume and therefore the working concentration, and it is stocked in 500mg and 1000mg. The nasal atomiser is the convenience option, arriving with matched diluent and a metered actuator for consistent delivery volume.
HOW SHOULD IT BE STORED AFTER RECONSTITUTION?
Keep the bottle refrigerated at 2–8°C and protected from light both before and after reconstitution. Once reconstituted, use within an appropriate research timeframe — material in solution has a materially shorter usable life than the sealed lyophilized form.
HOW IS IT SHIPPED IN CANADA?
Orders placed and paid before 5:00 PM EST ship the same business day via Canada Post Xpresspost with full tracking. Shipping is domestic from within Canada, so there are no customs delays or border holds.
IS THE COA VERIFIABLE?
Yes. Every batch is Janoshik-tested with a unique report key you can confirm independently — see our guide on how to verify a Janoshik unique key.
For laboratory research use only.
Not for human or veterinary use.
Not intended for diagnosis, treatment, cure, or prevention of any disease.
Use only in controlled laboratory settings by qualified personnel following appropriate safety procedures.





















































