SNAP-8 (Acetyl Octapeptide-3) — 10mg

SNAP-8 (Acetyl Octapeptide-3) is a synthetic octapeptide derived from the N-terminal region of SNAP-25, a core protein of the SNARE complex that governs vesicle-mediated neurotransmitter release. It is a two-residue extension of Acetyl Hexapeptide-8 (Argireline) and is studied as a competitive, reversible modulator of SNARE complex assembly — mechanistically distinct from agents that cleave SNAP-25 irreversibly. Best known as a topical cosmetic ingredient, it remains a standard reference peptide in expression-line and dermal formulation research.

BENEFITS

• Expression-line research — studied for effects on dynamic wrinkle depth in topical models

• SNARE-complex modulation — competes with SNAP-25 during vesicle docking assembly

• Reversible mechanism — competitive occupancy rather than proteolytic cleavage

• Topical formulation — water-soluble and stable across common cosmetic research bases

• Argireline comparison — the standard side-by-side reference for Acetyl Hexapeptide-8

WHAT RESEARCHERS LOOK AT

• Wrinkle-depth and periorbital line measurement across 28-day protocols

• SNARE complex assembly and presynaptic vesicle docking kinetics

• Catecholamine and neurotransmitter release in cell-based assays

• Comparative potency versus Acetyl Hexapeptide-8 (Argireline)

• Percutaneous penetration and peptide stability in topical carrier systems

QUICK SPECS

• Form: Lyophilized peptide

• Net per vial: 10 mg

• Purity: ≥99% (HPLC verified)

• Identity: MS-verified (per COA)

• Storage: 2–8°C short-term, -20°C long-term, protect from light and moisture

• Reconstitution: Use bacteriostatic water (sold separately)

IDENTITY BASICS

• Sequence: Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH₂ (octapeptide)

• Molecular Formula: C₄₁H₇₀N₁₆O₁₆S

• Molecular Weight: 1075.2 g/mol

• CAS Number: 868844-74-0

• Common Synonyms: SNAP-8, Acetyl Octapeptide-3, Acetyl Glutamyl Heptapeptide-1

WHY CHOOSE DURHAM PEPTIDES?

• Janoshik tested with independently verifiable COA keys

• Same-day shipping across Canada (orders before 5:00 PM EST)

• Free shipping on orders over $200 CAD

• 100% vegan — synthetically manufactured, no animal derivatives

• Secure payment via Interac e-Transfer, credit/debit, or Crypto

• Domestic Canadian supplier — no customs delays or international seizures

• For laboratory research use only.

• Not for human or veterinary use.

• Not intended for diagnosis, treatment, cure, or prevention of any disease.

• Use only in controlled laboratory settings by qualified personnel following appropriate safety procedures.