Retatrutide – 10mg
Research-grade Retatrutide (LY-3437943), a synthetic triple GLP-1/GIP/glucagon receptor agonist peptide studied for advanced metabolic research. 10mg lyophilized powder, 99%+ purity verified by Janoshik Analytical via HPLC and mass spectrometry. CAS 2381089-83-2.
For laboratory research use only.
Not for human or veterinary use.
Not intended for diagnosis, treatment, cure, or prevention of any disease.
Use only in controlled laboratory settings by qualified personnel following appropriate safety procedures.
Retatrutide (LY-3437943) is a synthetic triple-receptor agonist peptide that Durham Peptides supplies as research-grade 10 mg lyophilized vials, stocked and shipped domestically for researchers across Canada. It acts on three metabolic pathways at once — GLP-1, GIP, and glucagon — and is sometimes informally called "GLP-3" for this three-receptor mechanism.
Because it engages an additional glucagon pathway beyond dual-agonist compounds, retatrutide is frequently studied alongside Semaglutide (a mono-agonist) and Tirzepatide (a dual-agonist) to compare multi-receptor pharmacology. Durham Peptides stocks all three for comparative research.
BENEFITS
Triple receptor activation — studied for simultaneous GLP-1, GIP, and glucagon engagement
Metabolic research — explored in Phase 2 clinical trials with notable body-composition results
Glucagon component — linked to thermogenesis and energy-expenditure pathways
Next-generation compound — investigated as an advancement over dual-agonist approaches
Comparative pharmacology — assessed alongside mono- and dual-agonists in research settings
WHAT RESEARCHERS LOOK AT
Triple-agonist binding affinity across GLP-1, GIP, and glucagon receptors
Additive effects of glucagon-receptor activation on energy expenditure
Dose-response and tolerability profiling from clinical-trial data
Comparative outcomes vs tirzepatide and semaglutide
Pharmacokinetic profiling and receptor selectivity
QUICK SPECS
Form: Lyophilized peptide powder
Net per vial: 10 mg
Purity: ≥99% (HPLC verified)
Identity: MS-verified (per COA)
Storage: 2–8°C, protect from light and moisture
Reconstitution: Use bacteriostatic water (sold separately)
IDENTITY BASICS
CAS: 2381089-83-2
Classification: Triple GLP-1/GIP/glucagon receptor agonist
WHY CHOOSE DURHAM PEPTIDES FOR RETATRUTIDE?
Janoshik tested with independently verifiable COA keys
Same-day shipping across Canada (orders before 5:00 PM EST)
Free shipping on orders over $200 CAD
100% vegan — synthetically manufactured, no animal derivatives
Secure payment via Interac e-Transfer, credit/debit, or Crypto
Transparent Canadian pricing, shown above in CAD
SELECTED RESEARCH
IS RETATRUTIDE APPROVED IN CANADA?
No. Retatrutide remains an investigational compound in Phase 3 clinical trials and is not approved by Health Canada for human or veterinary use. Durham Peptides supplies it strictly as a research-use-only reference material for qualified laboratory researchers.
HOW MUCH DOES RETATRUTIDE COST IN CANADA?
Current pricing for retatrutide 10 mg is shown above in Canadian dollars, with Single Vial and 10-Pack options. Durham Peptides prices retatrutide in the middle of the Canadian market range, reflecting Janoshik-verified testing, domestic cold storage, and same-day Canadian shipping.
HOW IS RETATRUTIDE SHIPPED IN CANADA?
Orders placed and paid before 5:00 PM EST ship the same business day via Canada Post Xpresspost with full tracking. Because Durham Peptides ships from within Canada, there are no customs delays, border holds, or international transit that can degrade peptide quality.
HOW SHOULD RETATRUTIDE BE STORED AND RECONSTITUTED?
Store the lyophilized vial at 2–8°C, protected from light and moisture. For research handling, reconstitute with bacteriostatic water (sold separately). Once reconstituted, keep refrigerated and use within an appropriate research timeframe.
RETATRUTIDE VS TIRZEPATIDE VS SEMAGLUTIDE — WHAT'S THE DIFFERENCE?
Semaglutide is a single-receptor (GLP-1) agonist, tirzepatide is a dual GLP-1/GIP agonist, and retatrutide is a triple GLP-1/GIP/glucagon agonist. The added glucagon activity is the primary structural difference researchers study when comparing the three.
HOW DO I VERIFY THE CERTIFICATE OF ANALYSIS?
Every batch is tested by Janoshik Analytical and issued a unique report key. You can confirm authenticity independently — see our guide on how to verify a Janoshik unique key.
For laboratory research use only.
Not for human or veterinary use.
Not intended for diagnosis, treatment, cure, or prevention of any disease.
Use only in controlled laboratory settings by qualified personnel following appropriate safety procedures.
