NAD+ — 500mg
Research-grade NAD+ (nicotinamide adenine dinucleotide, oxidized form), a coenzyme central to cellular energy metabolism, redox signaling, and sirtuin-mediated longevity pathways. 500mg lyophilized powder, 99%+ purity verified by Janoshik Analytical via HPLC and mass spectrometry.
For laboratory research use only.
Not for human or veterinary use.
Not intended for diagnosis, treatment, cure, or prevention of any disease.
Use only in controlled laboratory settings by qualified personnel following appropriate safety procedures.
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every living cell, essential for over 500 enzymatic reactions including cellular respiration, DNA repair, and gene expression. It serves as a critical electron carrier in mitochondrial oxidative phosphorylation and is the primary substrate for sirtuin enzymes (SIRT1-7) and PARP enzymes involved in DNA damage response. Research interest in NAD+ has expanded dramatically due to observations that intracellular NAD+ levels decline with age, correlating with metabolic dysfunction in preclinical aging models. Durham Peptides also carries 5-Amino-1MQ, a small molecule NNMT inhibitor studied for its role in NAD+ salvage pathway modulation.
BENEFITS
Energy metabolism — essential cofactor in glycolysis, the TCA cycle, and oxidative phosphorylation
Longevity research — required substrate for sirtuin enzymes (SIRT1-7) studied in aging
DNA repair — consumed by PARP enzymes during poly(ADP-ribose)ylation of damaged DNA
Redox biology — central electron carrier in cellular NAD+/NADH redox balance
Broad research utility — applicable across metabolic, aging, neurological, and mitochondrial research
WHAT RESEARCHERS LOOK AT
NAD+/NADH ratio changes in metabolic disease and aging models
Sirtuin-dependent deacetylation and gene silencing pathways
PARP-mediated DNA repair responses and NAD+ depletion in cellular stress
Mitochondrial bioenergetics and Complex I electron transport
NAD+ supplementation effects on cellular senescence markers
