NAD+ — 500mg
Research-grade NAD+ (nicotinamide adenine dinucleotide, oxidized form), a coenzyme central to cellular energy metabolism, redox signaling, and sirtuin-mediated longevity pathways. 500mg lyophilized powder, 99%+ purity verified by an independent third-party lab via HPLC and mass spectrometry.
For laboratory research use only.
Not for human or veterinary use.
Not intended for diagnosis, treatment, cure, or prevention of any disease.
Use only in controlled laboratory settings by qualified personnel following appropriate safety procedures.
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every living cell, essential for over 500 enzymatic reactions including cellular respiration, DNA repair, and gene expression. It serves as a critical electron carrier in mitochondrial oxidative phosphorylation and is the primary substrate for sirtuin enzymes (SIRT1-7) and PARP enzymes involved in DNA damage response. Research interest in NAD+ has expanded dramatically due to observations that intracellular NAD+ levels decline with age, correlating with metabolic dysfunction in preclinical aging models. Durham Peptides also carries 5-Amino-1MQ, a small molecule NNMT inhibitor studied for its role in NAD+ salvage pathway modulation.
BENEFITS
Energy metabolism — essential cofactor in glycolysis, the TCA cycle, and oxidative phosphorylation
Longevity research — required substrate for sirtuin enzymes (SIRT1-7) studied in aging
DNA repair — consumed by PARP enzymes during poly(ADP-ribose)ylation of damaged DNA
Redox biology — central electron carrier in cellular NAD+/NADH redox balance
Broad research utility — applicable across metabolic, aging, neurological, and mitochondrial research
WHAT RESEARCHERS LOOK AT
NAD+/NADH ratio changes in metabolic disease and aging models
Sirtuin-dependent deacetylation and gene silencing pathways
PARP-mediated DNA repair responses and NAD+ depletion in cellular stress
Mitochondrial bioenergetics and Complex I electron transport
NAD+ supplementation effects on cellular senescence markers
QUICK SPECS
Form: Lyophilized powder
Net per vial: 500 mg
Purity: ≥99% (HPLC verified)
Identity: MS-verified (per COA)
Storage: -20°C recommended, protect from light and moisture
Reconstitution: Use bacteriostatic water or sterile water (sold separately)
IDENTITY BASICS
Full Name: Nicotinamide adenine dinucleotide (oxidized form)
Molecular Formula: C₂₁H₂₇N₇O₁₄P₂
Molecular Weight: 663.43 g/mol
CAS Number: 53-84-9
PubChem CID: 5893
Note: NAD+ is a dinucleotide coenzyme, not a peptide. It is carried alongside research peptides due to its relevance in metabolic and longevity research protocols.
WHY CHOOSE DURHAM PEPTIDES FOR NAD+?
independently lab-tested with verifiable COA keys
Same-day shipping across Canada (orders before 5:00 PM EST)
Free shipping on orders over $200 CAD
Secure payment via Interac e-Transfer, credit/debit, or Crypto
SELECTED RESEARCH
Yoshino et al. — NAD+ intermediates: the biology and therapeutic potential of NMN and NR: https://pubmed.ncbi.nlm.nih.gov/29211728/
Verdin — NAD+ in aging, metabolism, and neurodegeneration: https://pubmed.ncbi.nlm.nih.gov/25540137/
Rajman et al. — Therapeutic potential of NAD-boosting molecules: https://pubmed.ncbi.nlm.nih.gov/29295624/
WHAT IS NAD+?
Nicotinamide adenine dinucleotide is a coenzyme present in every living cell, central to cellular redox reactions and a required substrate for the sirtuin and PARP enzyme families. It is studied extensively in longevity, mitochondrial and metabolic research. Unlike the peptides in our catalogue it is a dinucleotide rather than an amino-acid chain.
IS NAD+ AVAILABLE AS A NASAL SPRAY?
Yes. NAD+ Nasal Spray — 500mg supplies the same research-grade material in a 10 mL metered atomiser that delivers 0.1 mL per actuation. It ships unmixed with its own sterile diluent, so the researcher reconstitutes it on arrival rather than receiving a bottle that has been sitting pre-diluted. The vials remain the flexible format — you set the reconstitution volume and therefore the working concentration. The atomiser is the repeatable one.
WHAT IS THE DIFFERENCE BETWEEN THE 500MG AND 1000MG VIALS?
Quantity of lyophilized material only. Both are the same compound held to the same purity standard and the same batch testing regime; the 1000mg vial lowers the per-milligram cost for larger or longer protocols.
WHAT IS THIS VIAL RECONSTITUTED WITH?
Bacteriostatic water, which is sold separately in our catalogue. The lyophilized powder is stable as shipped; once in solution its usable life shortens considerably, which is why it ships dry. Our nasal sprays differ on this point — each one includes its own sterile diluent, preserved with 0.3% potassium sorbate.
HOW SHOULD IT BE STORED?
Sealed and lyophilized, store at 2–8°C away from light; for long-term storage, −20°C is better. NAD+ is notably light- and moisture-sensitive, so keep the vial sealed until use. After reconstitution keep it refrigerated at 2–8°C and use it within an appropriate research timeframe.
IS THE COA VERIFIABLE?
Yes. Every batch is independently lab-tested with a unique report key you can confirm independently — see our guide on how to verify a lab report key.
HOW FAST DOES IT SHIP IN CANADA?
Orders placed and paid before 5:00 PM EST ship the same business day via Canada Post Xpresspost with full tracking. Shipping is domestic from within Canada, so there are no customs delays or border holds.
For laboratory research use only.
Not for human or veterinary use.
Not intended for diagnosis, treatment, cure, or prevention of any disease.
Use only in controlled laboratory settings by qualified personnel following appropriate safety procedures.
Volume discounts apply to your whole order, not to a single item. Enter the code at checkout.
Spend $200 or more — 10% off with code VOLUME10
Spend $500 or more — 15% off with code VOLUME15
Spend $1,000 or more — 20% off with code VOLUME20
The thresholds are worth more than they look. A $499 order costs you $449. Add one more $20 vial to reach $500 and you pay $425 — more product, $24 less. Free shipping over $200.
Ordering at volume? The full catalogue is available at wholesale pricing through a five-tier programme.
Minimum 10 units per product, any mix of products in one order
Accounts open at $2,000 per order
Tiers are set on 12-month volume and move up automatically
Canadian stock, same-day dispatch, shipping included
Apply at durhampeptides.ca/wholesale and we come back within one business day. Single vials and multi-packs on this page are available to everyone at the prices shown — no account needed.
