Kisspeptin-10 — 10mg

Kisspeptin-10 (KP-10) is the shortest fully active fragment of kisspeptin, a neuropeptide encoded by the KISS1 gene and cleaved from the 54-amino-acid precursor metastin. Acting on the G-protein-coupled receptor KISS1R (formerly GPR54), kisspeptin is a primary upstream regulator of GnRH neurons and is therefore a central tool in research on the hypothalamic–pituitary–gonadal axis. Its compact decapeptide structure retains the full receptor-binding activity of the longer parent peptides.

BENEFITS

• GnRH signaling — studied for upstream stimulation of gonadotropin-releasing hormone neurons

• KISS1R activation — investigated for agonist activity at the GPR54 receptor

• Reproductive endocrinology — explored as a tool in hypothalamic–pituitary–gonadal axis research

• Compact active fragment — retains full receptor activity of the parent kisspeptin

• Well-defined target — extensively characterized KISS1R research ligand

WHAT RESEARCHERS LOOK AT

• KISS1R (GPR54) receptor binding and downstream signaling

• Regulation of GnRH neuron activity and gonadotropin (LH/FSH) release

• Hypothalamic–pituitary–gonadal axis research models

• Pulsatile versus continuous exposure signaling dynamics

• Structure–activity relationships of the C-terminal decapeptide

QUICK SPECS

• Form: Lyophilized peptide

• Net per vial: 10 mg

• Purity: ≥99% (HPLC verified)

• Identity: MS-verified (per COA)

• Storage: 2–8°C short-term, -20°C long-term, protect from light and moisture

• Reconstitution: Use bacteriostatic water (sold separately)

IDENTITY BASICS

• Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂ (decapeptide)

• Molecular Formula: C₆₃H₈₃N₁₇O₁₄

• Molecular Weight: 1302.45 g/mol

• CAS Number: 374675-21-5

• Common Synonyms: KP-10, Kisspeptin-112–121, Metastin (45–54)

WHY CHOOSE DURHAM PEPTIDES?

• independently lab-tested with verifiable COA keys

• Same-day shipping across Canada (orders before 5:00 PM EST)

• Free shipping on orders over $200 CAD

• 100% vegan — synthetically manufactured, no animal derivatives

• Secure payment via Interac e-Transfer, credit/debit, or Crypto

• Domestic Canadian supplier — no customs delays or international seizures

• For laboratory research use only.

• Not for human or veterinary use.

• Not intended for diagnosis, treatment, cure, or prevention of any disease.

• Use only in controlled laboratory settings by qualified personnel following appropriate safety procedures.

Volume discounts apply to your whole order, not to a single item. Enter the code at checkout.

• Spend $200 or more — 10% off with code VOLUME10

• Spend $500 or more — 15% off with code VOLUME15

• Spend $1,000 or more — 20% off with code VOLUME20

The thresholds are worth more than they look. A $499 order costs you $449. Add one more $20 vial to reach $500 and you pay $425 — more product, $24 less. Free shipping over $200.

Ordering at volume? The full catalogue is available at wholesale pricing through a five-tier programme.

• Minimum 10 units per product, any mix of products in one order

• Accounts open at $2,000 per order

• Tiers are set on 12-month volume and move up automatically

• Canadian stock, same-day dispatch, shipping included

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