Kisspeptin-10 — 10mg
Research-grade Kisspeptin-10, a synthetic decapeptide (Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂) corresponding to the C-terminal active fragment of the KISS1 gene product. Studied for activation of the KISS1R (GPR54) receptor and its role in gonadotropin-releasing hormone signaling in reproductive-endocrinology research. 10mg lyophilized powder, 99%+ purity verified by Janoshik Analytical via HPLC and mass spectrometry.
For laboratory research use only.
Not for human or veterinary use.
Not intended for diagnosis, treatment, cure, or prevention of any disease.
Use only in controlled laboratory settings by qualified personnel following appropriate safety procedures.
Kisspeptin-10 (KP-10) is the shortest fully active fragment of kisspeptin, a neuropeptide encoded by the KISS1 gene and cleaved from the 54-amino-acid precursor metastin. Acting on the G-protein-coupled receptor KISS1R (formerly GPR54), kisspeptin is a primary upstream regulator of GnRH neurons and is therefore a central tool in research on the hypothalamic–pituitary–gonadal axis. Its compact decapeptide structure retains the full receptor-binding activity of the longer parent peptides.
BENEFITS
GnRH signaling — studied for upstream stimulation of gonadotropin-releasing hormone neurons
KISS1R activation — investigated for agonist activity at the GPR54 receptor
Reproductive endocrinology — explored as a tool in hypothalamic–pituitary–gonadal axis research
Compact active fragment — retains full receptor activity of the parent kisspeptin
Well-defined target — extensively characterized KISS1R research ligand
WHAT RESEARCHERS LOOK AT
KISS1R (GPR54) receptor binding and downstream signaling
Regulation of GnRH neuron activity and gonadotropin (LH/FSH) release
Hypothalamic–pituitary–gonadal axis research models
Pulsatile versus continuous exposure signaling dynamics
Structure–activity relationships of the C-terminal decapeptide
