Pinealon — 10mg
Research-grade Pinealon, a synthetic tripeptide (Glu-Asp-Arg) studied for neuroprotection, oxidative-stress modulation, and gene-expression research in the central nervous system. 10mg lyophilized powder, 99%+ purity verified by Janoshik Analytical via HPLC and mass spectrometry. CAS 175175-23-2.
For laboratory research use only.
Not for human or veterinary use.
Not intended for diagnosis, treatment, cure, or prevention of any disease.
Use only in controlled laboratory settings by qualified personnel following appropriate safety procedures.
Pinealon (also known as the EDR peptide) is a synthetic tripeptide with the sequence Glu-Asp-Arg. It belongs to the class of ultrashort peptide bioregulators developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology, and has been studied across preclinical models for neuroprotection, oxidative-stress modulation, and gene-expression regulation in the central nervous system.
BENEFITS
Neuroprotection — studied in neuronal cell models for protection against oxidative and excitotoxic stress
Oxidative stress — investigated for dose-dependent reduction of reactive oxygen species (ROS) accumulation
Apoptosis modulation — examined for effects on proapoptotic markers such as caspase-3 and p53
Gene expression — modeled as a short-peptide regulator interacting with promoter regions of neuroprotective genes
Single-compound simplicity — short tripeptide structure, well-characterized in published literature
WHAT RESEARCHERS LOOK AT
ROS suppression in cerebellar granule cells, cortical neurons, and PC12 cell cultures
Caspase-3 and p53 activation under oxidative and excitotoxic conditions
MAPK/ERK signaling pathway modulation and cell-cycle effects
Antioxidant enzyme expression (SOD2, GPX1, catalase) in neuronal models
Dendritic spine preservation in Alzheimer's- and Huntington's-model preparations
