SS-31 (Elamipretide) — 10mg
Research-grade SS-31 (Elamipretide), a synthetic mitochondria-targeting tetrapeptide (D-Arg-Dmt-Lys-Phe-NH₂) that selectively associates with cardiolipin on the inner mitochondrial membrane. Studied for its effects on mitochondrial bioenergetics, electron transport efficiency, and reactive oxygen species in cellular models. 10mg lyophilized powder, 99%+ purity verified by Janoshik Analytical via HPLC and mass spectrometry.
For laboratory research use only.
Not for human or veterinary use.
Not intended for diagnosis, treatment, cure, or prevention of any disease.
Use only in controlled laboratory settings by qualified personnel following appropriate safety procedures.
SS-31, also known as elamipretide (MTP-131), is a cell-permeable aromatic-cationic tetrapeptide that concentrates in the inner mitochondrial membrane, where it binds the phospholipid cardiolipin. By stabilizing cardiolipin and the cristae architecture it supports, SS-31 is widely used as a research tool for probing mitochondrial electron transport, ATP synthesis, and oxidative stress. Its D-amino acid and dimethyltyrosine (Dmt) residues confer resistance to peptidase degradation.
BENEFITS
Mitochondrial bioenergetics — studied for effects on electron transport chain efficiency and ATP synthesis
Cardiolipin interaction — investigated for selective binding to inner-membrane cardiolipin and cristae stabilization
Oxidative stress research — explored for modulation of mitochondrial reactive oxygen species
Peptidase-resistant design — D-arginine and dimethyltyrosine residues confer metabolic stability
Cell-permeable — aromatic-cationic structure enables mitochondrial accumulation without a carrier
WHAT RESEARCHERS LOOK AT
Cardiolipin binding and inner mitochondrial membrane cristae morphology
Electron transport chain coupling and ATP production efficiency
Mitochondrial reactive oxygen species generation under stress conditions
Ischemia–reperfusion and tissue-injury cellular models
Age-associated decline in mitochondrial function
